Browsing by Subject "genetic conservation"
Now showing items 1-5 of 5
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Article
Binding free energies and free energy components from molecular dynamics and Poisson-Boltzmann calculations. Application to amino acid recognition by aspartyl-tRNA synthetase
(2001)Specific amino acid binding by aminoacyl-tRNA synthetases (aaRS) is necessary for correct translation of the genetic code. Engineering a modified specificity into aminoacyl-tRNA synthetases has been proposed as a means to ...
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Article
The identification and characterization of KRAB-domain-containing zinc finger proteins
(1992)The zinc finger motif is a highly conserved tandemly repeated sequence of 28-30 amino acids that was first identified in transcription factor TFIIIA from Xenopus laevis. Subsequently, similar motifs were found and characterized ...
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Article
MicroRNAs: A newly described class of encoded molecules that play a role in health and disease
(2010)14(4): 236-240.
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Article
The pathogenic properties of a novel and conserved gene product, KerV, in proteobacteria
(2009)Identification of novel virulence factors is essential for understanding bacterial pathogenesis and designing antibacterial strategies. In this study, we uncover such a factor, termed KerV, in Proteobacteria. Experiments ...
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Article
Retinoid X receptor-γ gene expression is developmentally regulated in the embryonic rodent peripheral nervous system
(1998)The retinoid X receptor-γ (RXRγ) is a transcription factor that belongs to the thyroid hormone/retinoid family of nuclear receptors. Previous studies have shown that RXRγ is expressed in the developing peripheral nervous ...